. 2011 Jul 19;12:64. doi: 10.1186/1471-2156-12-64

Table 5.

Scenarios that could occur across the genome with the optimal method of selection.

	Structured Phenotype (K₁≠ K₂)	Non-Structured Phenotype (K₁= K₂)
Structured Genotype (p₁≠ p₂)	Any method of selection except no PC adjustment	Selecting a fixed number of PCs or PCs associated with the SNP

Non-Structured Genotype (p₁= p₂)	Selecting PCs associated with the SNP (α = 0.01), 10% Rule, no PC adjustment	Any method of selection

p₁and p₂are the allele frequencies in population 1 and 2, respectively. K₁and K₂are the frequency of disease in population 1 and 2, respectively.