Table 6.

ADVERSE EVENTS

	N (%) Total = 63
EVENT	ALL SUBJECTS	PLACEBO (32)	CALCITONIN (31)	p
CLINICAL
All effects	14 (22.2%)	5 (15.6%)	9 (29%)	0.20
Epistaxis	5 (7.9%)	3 (9.4%)	2 (6.5%)	0.67
Irritation of the upper respiratory tract	4 (6.3%)	2 (6.3%)	2 (6.5%)	0.97
Rhinitis	4 (6.3%)	1 (3.1%)	3 (9.7%)	0.29
Nasal mucosa wound	2 (3.2%)	1 (3.1%)	1 (3.2%)	0.98
Headache	2 (3.2%)	2 (6.3%)	0 (0%)	0.16
Allergic reaction	2 (3.2%)	1 (3.1%)	1 (3.2%)	0.98
Decreased appetite	2 (3.2%)	1 (3.1%)	1 (3.2%)	0.98
Back pain	2 (3.2%)	2 (6.3%)	0 (0%)	0.16
Fatigue	2 (3.2%)	1 (3.1%)	1 (3.2%)	0.98
Infection of nasal tissue	1 (1.6%)	0 (0%)	1 (3.2%)	0.31
Seizure	1 (1.6%)	0 (0%)	1 (3.2%)	0.31
Eye irritation	1 (1.6%)	1 (3.1%)	0 (0%)	0.32
Nausea	1 (1.6%)	0 (0%)	1 (3.2%)	0.31
Abdominal pain	1 (1.6%)	0 (0%)	1 (3.2%)	0.31
Arthralgia	1 (1.6%)	1 (3.1%)	0 (0%)	0.32
LABORATORY
Elevated PTH (serum PTH > 65….)	8 (16%)	3 (12.5%)	5 (19.2%)	0.52
Hypocalcemia (serum Ca < 8….)	1 (1.6%)	1 (3.1%)	0 (0%)	0.32