. Author manuscript; available in PMC: 2012 Aug 10.

Published in final edited form as: J Am Chem Soc. 2011 Jul 18;133(31):12293–12297. doi: 10.1021/ja2049012

Table 3.

Catalytic Enantioselective [3+2] Cycloadditions of γ-Substituted Allenes with a Phthalimide-Substituted Olefin^a


entry	R	ee (%)	yield (%)^b
1	Me	98	81
2		98	72
3		98	86

All data are the average of two experiments. For the determination of structure, including stereochemistry, see the Supporting Information.

Yield of purified product; for each cycloaddition, the ratio of regioisomers and diastereomers is ≥20:1 (determined by ¹H NMR analysis of the unpurified reaction mixture).