Table 2. Summary of SNP QC.
QC threshold | Removed SNPs | SNPs removed solely for that reason* | |
Starting point | 760,053 ** | ||
Hardy-Weinberg equilibrium, p<10−6 | 1,061 | 45 | |
Genotyping rate<.95 | CAHRES | 196,644 | 668 |
CAPS | 439,509 | 25,839 | |
DGI | 401,945 | 6,014 | |
SCZ-SW | 396,702 | 9,941 | |
TWINGENE-SW | 273,685 | 1,975 | |
EIRA | 349,059 | 27,371 | |
Minor allele frequency<.01 | 8,311 | 70 | |
Between-study comparison (1-vs-rest comparison), any p<10−6 | 142,899 | 785 | |
Remaining | 184,449 |
*SNPs that were not removed due to any other criterion than the one listed.
**The number of SNPs in the largest study (SCZ-SW). All other numbers refer to this number and not the number of SNPs available in each study.