Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2011 Aug 4;6(8):e22764. doi: 10.1371/journal.pone.0022764

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Kiok et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

The activity of RPTP-LAR remained at a basal activity level in the control and in Liprin-α4 knock-down line 323. In the presence of nickel, Liprin-α4 binds to the second phosphatase domain (D2) of RPTP-LAR. By reorganization of RPTP-LAR, the first phosphatase domain (D1) might undergo conformational arrangements and become more open for its phosphate substrates.