Table 3.
Second trimester intake of trans fatty acids in relation to risk of severe preeclampsia Danish National Birth Cohort, 1998–2003 (n = 67,186 pregnancies).
| Quintile of Intake | ||||||
|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | p, trend 1 | |
| Industrial trans fats, range (g/day) | < 0.25 | 0.25 – 0.37 | 0.38 – 0.51 | 0.52 – 0.72 | ≥0.73 | |
| Cases / Pregnancies | 71 / 13,437 | 98 / 13,437 | 71 / 13,438 | 85 / 13,437 | 77 / 13,437 | |
| Age and energy-adjusted RR | 1.00 | 1.38 (1.02, 1.88) | 1.01 (0.72, 1.40) | 1.20 (0.88, 1.65) | 1.09 (0.79, 1.51) | 0.91 |
| Multivariate-adjusted RR 2 | 1.00 | 1.43 (1.05, 1.95) | 1.05 (0.75, 1.47) | 1.29 (0.94, 1.79) | 1.18 (0.85, 1.64) | 0.69 |
| Ruminant trans fats, range (g/day) | < 1.06 | 1.06 – 1.33 | 1.34 – 1.62 | 1.63 – 1.99 | ≥2.00 | |
| Cases / Pregnancies | 84 / 13,437 | 91 / 13,437 | 88 / 13,438 | 71 / 13,437 | 68 / 13,437 | |
| Age and energy-adjusted RR | 1.00 | 1.09 (0.81, 1.46) | 1.05 (0.78, 1.41) | 0.85 (0.62, 1.17) | 0.82 (0.59, 1.12) | 0.06 |
| Multivariate-adjusted RR 2 | 1.00 | 1.14 (0.85, 1.54) | 1.14 (0.84, 1.54) | 0.98 (0.71, 1.35) | 1.01 (0.73, 1.41) | 0.75 |
| Total trans fats, range (g/day) | < 1.48 | 1.48 – 1.82 | 1.83 – 2.15 | 2.16 – 2.58 | ≥2.59 | |
| Cases / Pregnancies | 89 / 13,437 | 83 / 13,437 | 87 / 13,438 | 68 / 13,437 | 75 / 13,437 | |
| Age and energy-adjusted RR | 1.00 | 0.93 (0.69, 1.25) | 0.98 (0.73, 1.32) | 0.77 (0.56, 1.05) | 0.84 (0.62, 1.15) | 0.15 |
| Multivariate-adjusted RR 2 | 1.00 | 1.00 (0.74, 1.35) | 1.11 (0.82, 1.50) | 0.89 (0.64, 1.23) | 1.07 (0.78, 1.48) | 0.92 |
1
Calculated in a separate regression model where the median intake in each category was modeled as a continuous variable
2
Adjusted for age, total energy intake, pre-pregnancy BMI, height, parity, smoking status, education and year of pregnancy.