Table 4.
Second trimester intake of trans fatty acids in relation to risk of preeclampsia and severe preeclampsia according to pre-pregnancy characteristics and year of pregnancy. Danish National Birth Cohort, 1998 – 2003 (n = 67,186 pregnancies) 1
| Cases | Industrial trans fats | Ruminant trans fats | |||
|---|---|---|---|---|---|
| RR (95% CI) per 1 g/day | P, interaction | RR (95% CI) per 1g/day | P, interaction | ||
| Preeclampsia | |||||
| Age < 30 years | 1,088 | 1.01 (0.84, 1.21) | 0.49 | 0.91 (0.81, 1.02) | 0.26 |
| Age ≥ 30 years | 716 | 1.13 (0.89, 1.40) | 1.00 (0.88, 1.15) | ||
| BMI < 25 kg/m2 | 1,071 | 1.03 (0.86, 1.23) | 0.76 | 0.97 (0.87, 1.08) | 0.45 |
| BMI ≥ 25 kg/m2 | 733 | 1.08 (0.86, 1.35) | 0.91 (0.79, 1.04) | ||
| Nulliparous | 1,297 | 1.06 (0.90, 1.24) | 0.86 | 0.96 (0.87, 1.06) | 0.61 |
| Parous | 507 | 1.03 (0.79, 1.35) | 0.91 (0.78, 1.07) | ||
| 1998 – 1999 | 637 | 1.04 (0.84, 1.27) | 0.80 | 1.00 (0.88, 1.14) | 0.63 |
| 2000 – 2001 | 798 | 1.04 (0.83, 1.30) | 0.88 (0.78, 0.99) | ||
| 2002 – 2003 | 369 | 1.14 (0.81, 1.59) | 1.00 (0.82, 1.22) | ||
| Severe preeclampsia | |||||
| Age < 30 years | 238 | 0.98 (0.65, 1.47) | 0.24 | 0.90 (0.70, 1.16) | 0.33 |
| Age ≥ 30 years | 164 | 1.39 (0.91, 2.12) | 1.07 (0.84, 1.36) | ||
| BMI < 25 kg/m2 | 266 | 1.06 (0.74, 1.51) | 0.59 | 0.95 (0.76, 1.19) | 0.77 |
| BMI ≥ 25 kg/m2 | 136 | 1.25 (0.74, 2.13) | 1.01 (0.75, 1.35) | ||
| Nulliparous | 310 | 1.03 (0.72, 1.48) | 0.34 | 1.02 (0.82, 1.26) | 0.26 |
| Parous | 92 | 1.40 (0.83, 2.36) | 0.81 (0.57, 1.16) | ||
| 1998 – 1999 | 136 | 1.23 (0.82, 1.86) | 0.45 | 0.97 (0.73, 1.28) | 0.81 |
| 2000 – 2001 | 186 | 1.11 (0.66, 1.86) | 0.95 (0.72, 1.24) | ||
| 2002 – 2003 | 80 | 0.80 (0.38, 1.68) | 1.03 (0.68, 1.57) | ||
1
All models are adjusted for age, total energy intake, pre-pregnancy BMI, height, parity, smoking status, education and year of pregnancy.