Table 1.

Effect of Casp8p41 expression on selected cytokine production by primary CD4 T cells.

Cytokine	HA	HACasp8p41	HACasp8p41ΔDED	P
IL-1b	0.110191	0.145075	0.13917596	NS
IL-1RA	11.30055	36.976	16.58867749	0.01
IL-2	1.23846	8.822	2.997907704	0.05
IL-4	0.096106	0.1244	0.09045644	NS
IL-5	0.378586	0.149585	0.177616927	NS
IL-6	1.08943	0.344145	0.637830346	NS
IL-7	0.0250765	0.07095	0.03242824	0.08
IL-8	47.34095	35.7715	61.4376208	NS
IL-9	2.33828	2.49515	2.166054085	NS
IL-10	18.5535	21.516	16.83512521	NS
IL-12p70	0.59533	0.30721	0.394373528	NS
IL-13	5.38405	1.9784	3.006429702	NS
IL-15	0.03536	0.08541	0.051772573	0.03
IL-17	5.98745	3.62965	4.95092198	NS
Eotaxin	0.2799795	0.47365	0.348581184	NS
FGF-basic	0.3101295	0.7034	0.306851611	NS
GCFS	0.2037355	0.42731	0.215285777	NS
GM-CSF	3.35514	2.5599	3.268170728	0.05
IFN-γ	85.9545	35.554	66.5147637	0.08
IP-10	818.12	571.95	551.2636505	NS
MCP-1	0.07225	0.117345	0.08004584	NS
MIP-1a	64.2785	119.045	70.45258705	NS
MIP-1b	160.4445	147.87	113.2748765	NS
PDGF-BB	1.2001	2.789	1.351000266	NS
Rantes	358.2155	328.055	249.9843041	NS
TNF-α	123.9105	331.24	178.5089302	0.005
VEGF	15.0265	7.2425	10.50087123	NS

Mean cytokine amounts (pg/cell) produced by cells expressing empty vector (HA), HACasp8p41 or Casp8p41 missing the tandem death effector domains (HACaspp8p41ΔDED) are shown.