Fig. 5.
MYC/MAX heterodimers were detected in secondary AS tumors (RT-BR, post-radiation breast; PL, post-lymphedema), MYC amplified SKBR3 and MYC-transfected NIH3T3 cells, but not in primary AS (BR, primary breast AS) and GIST cell line. AS tumor lysates were co-IP with anti-MAX antibody and the immunoprecipitates were detected with anti-MYC and anti-MAX antibodies separately. MAX was detected in all tested samples.