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. Author manuscript; available in PMC: 2011 Aug 4.
Published in final edited form as: Nature. 2010 Dec 15;469(7329):245–249. doi: 10.1038/nature09585

Figure 2. ATM and γ-H2AX regulate DNA end resection.

Figure 2

pMX-DELCJ Southern blot analysis (as described in Fig. 1 a and b) of STI571-treated (a) Lig IV−/−:H2AX−/−:DELCJ abl pre-B cells reconstituted with an empty retroviral vector (empty) or vectors encoding wild-type H2AX (H2AX) or H2AXS139A and (b) Artemis−/−:DELCJ and Artemis−/−:H2AX−/−:DELCJ abl pre-B cell lines treated with either the ATM inhibitor KU55933 (+) or a DMSO vehicle control (−).