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. Author manuscript; available in PMC: 2011 Oct 1.
Published in final edited form as: J Orthop Res. 2011 Mar 29;29(10):1521–1527. doi: 10.1002/jor.21408

Fig. 5.

Fig. 5

BMMs with decreased SH3BP2 expression fail to differentiate into mature osteoclasts. The number of TRAP+, multinucleated (MN) osteoclasts (OCs) derived from BMMs with decreased SH3BP2 expression was significantly fewer than controls (42% of that with empty vector and 44% of that with scramble shRNA, *p<0.0001 compared with both controls). The surface area occupied by the TRAP+, multinucleated (MN) osteoclasts (OCs) was reduced in SH3BP2 shRNA infected BMMs compared to control infections (24% of that with both empty and scramble shRNA, **p<0.0001 compared with both controls).