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Effect of Designed Sulfated Benzofurans on Human Plasma Clotting Time.a
| APPT | PT | |
|---|---|---|
| (μM) | (μM) | |
| 5i | 1,250 | 1,200 |
| 5g | >1,200 | neb |
| 5c | >2,000 | ne |
| 12a | 740 | 2,100 |
| 12b | >1,000 | 850 |
| 12c | 355 | ne |
| 12d | >1,000 | ne |
| 12e | 530 | ne |
| 14 | >1,000 | ndc |
| 15 | >1,000 | ne |
PT and APTT values were deduced in in vitro human plasma experiments where the clot initiator is either thromboplastin or ellagic acid, respectively. See Methods for details.
no effect.
not determined.
