Table 1.

Studies evaluating the MitraClip device

Study	Population	n
EVEREST I1 (feasibility)	Non-randomized	55
EVEREST II1	Pre-randomization	60
EVEREST II2	High risk registry	78
EVEREST II3 (pivotal)	Randomized patients (2:1 MitraClip to surgery)	279, 184 (MitraClip)
REALISM (continued access)	High risk & non-high risk	549
European experience	Commercial	2 113
Total		3 039 (MitraClip)

Data complete to 28th Mar., 2011

¹Feldman et al., 2009

²Kar et al., 2011

³Feldman et al., 2011