Table 1.
Time | Group | HR (beat/min) | LVSP (mmHg) | LVEDP (mmHg) |
Before AMI | Sham | 115±5 | 128±3.5 | 4.5±1.3 |
Control | 122±8 | 126±5.6 | 4.1±1.1 | |
Lipo-PGE1 | 113±9 | 127±2.8 | 4.2±2.1 | |
AMI 2 h | Sham | 115±5 | 128±3.5 | 4.5±1.3 |
Control | 127±7 | 103±2.5# | 7.2±2.2# | |
Lipo-PGE1 | 110±3 | 109±2.3# | 7.8±1.3# | |
Reperfusion 1 h | Sham | 115±5 | 128±3.5 | 4.5±1.3 |
Control | 122±6 | 105±3.0# | 6.6±1.6# | |
Lipo-PGE1 | 112±3 | 124±8.3*## | 5.6±1.0*## | |
Reperfusion 2 h | Sham | 115±5 | 128±3.5 | 4.5±1.3 |
Control | 121±9 | 108±3.5# | 6.4±2.2# | |
Lipo-PGE1 | 114±2 | 131±8.9*## | 4.9±1.4*## | |
Reperfusion 3 h | Sham | 115±5 | 128±3.5 | 4.5±1.3 |
Control | 125±5 | 110±7.8# | 6.3±2.6# | |
Lipo-PGE1 | 113±6 | 130±3.3*## | 4.3±2.3*## |
LVSP, LVEDP and HR were obtained by catheter method at five time points: (1) before AMI; (2) 2 h after occlusion; (3) 1 h after reperfusion; (4) 2 h after reperfusion; and, (5) 3 h after reperfusion.
P<0.05 vs. the control group
P<0.05 vs. before AMI
P<0.05 vs. 2 h after AMI