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. Author manuscript; available in PMC: 2012 Feb 4.
Published in final edited form as: Nature. 2011 Jul 17;476(7358):92–95. doi: 10.1038/nature10206

Figure 3. Opn4Cre/+;Brn3Z-dta/+ mice show severe deficits in the pupillary light reflex PLR).

Figure 3

a–b, Representative images of PLR from control and Opn4Cre/+;Brn3bZ-dta/+ mice. Left panels show pupils under dark conditions, middle panels show pupils under low light intensity (22 μW/cm2) and right panels show pupils under high light intensity (5.66 mW/cm2). c, Quantification of PLR data from control (n=5) and Opn4Cre/+;Brn3bZ-dta/+ n=6) animals. ** indicates p<0.01 with 1-way ANOVA. Error bars represent SEMs.