Table 1.
Clinical, biochemical and serological characteristics of PBC patients.
| AMA+ | AMA− | All PBC patients | |
|---|---|---|---|
| Number of subjects | 11 | 4 | 15 |
| Mean age (years) | 68 (42–80) | 64 (46–75) | 67 (42–80) |
| Duration of disease (years) | 14 (4–28) | 15 (4–28) | 14 (4–28) |
| Liver cirrhosis (%) | 8 (53) | 4 (27) | 12 (80) |
| Total bilirubin (mg/dl) (n.v. < 1.0) | 0.61 ± 0.11 | 0.77 ± 0.29 | 0.66 ± 0.18 |
| Alkaline phosphatase (IU/l) (n.v. < 279) | 294 ± 175 | 736 ± 400 | 412 ± 311 |
| Alanine aminotransferase (U/l) (n.v. < 50) | 30 ± 6 | 59 ± 27 | 38 ± 19 |
| Albumin (g/dl) (n.v. > 3,5) | 4.41 ± 0.58 | 4.32 ± 0.18 | 4.39 ± 0.50 |
| IgG (mg/dl) (n.v. < 1700) | 1134 ± 179 | 1295 ± 134 | 1177 ± 180 |
| IgM (mg/dl) (n.v. < 280) | 289 ± 178 | 245 ± 109 | 277 ± 160 |
Mean values ± standard deviation unless otherwise stated.