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. 2011 Jul 20;31(29):10451–10462. doi: 10.1523/JNEUROSCI.0117-11.2011

Figure 7.

Figure 7.

Intraneuronal distribution of p35 and Cdk5 tagged proteins. At larval stage, p35-myc is enriched in soma, calyx, and peduncle (A, A′), while Cdk5-FLAG wild-type and Cdk5-FLAG dominant-negative forms have identical distribution patterns and are present through all parts of neuron (B, B′). At adult stage, p35-myc is enriched in soma, calyx, and AIS and present in axonal part at low level (C, C′). Cdk5 is enriched in soma and axonal part and present at lower level in calyx. D″, In adult brain, OECdk5DN has maintained larval phenotype and shifted up the Fas2 border (B″, D″, white arrowhead). The brackets combine images from the same brain. For schematic details, see the legends of Figures 1 and 4. Scale bar, 30 μm.