Regional rates of cerebral protein synthesis in WT (open bars) and KI (filled bars) mice. Bars represent the means ± SEM for eight mice in each group except for the dorsal motor nucleus of the vagus (10) with seven KI mice. Abbreviations are as follows: dHi, dorsal hippocampus; dCA1, CA1 sector of the pyramidal cell layer of dorsal hippocampus; dCA2&3, CA2&3 sectors of the pyramidal cell layer of dorsal hippocampus; dorsal dentate gyrus; vHi, ventral hippocampus; vCA1, CA1 sector of the pyramidal cell layer of ventral hippocampus; vCA2&3, CA2&3 sectors of the pyramidal cell layer of ventral hippocampus; ventral dentate gyrus; FrCx, frontal cortex; PFrCx, medial prefrontal cortex; SmCx, somatosensory cortex; PPCx, posterior parietal cortex; CbCx, cerebellar cortex; BSt, bed nucleus of the stria terminalis; Str, striatum; blA, basolateral amygdala; Th, thalamus; PVN, paraventricular nucleus of the hypothalamus; LHA, lateral hypothalamic area; CC, corpus callosum; 10, dorsal motor nucleus of the vagus. The two groups were compared by means of one-tailed student’s t-tests; *, 0.01 ≤ P ≤ 0.05; †, 0.05 ≤ P ≤ 0.10.