Figure 3.

Fitting of the model (CD4+ and CD8+ T cell populations) to the data. The black curves represent the best fit of our mathematical model to the data, while all the data are shown by red x. Panel A: total number of CD4+ T cells in the LN (Naïve CD4 [N₄]+ Precursor Th1 $\text{Th}1[{\widehat{\mathrm{T}}}_1^{\text{LN}}]+\text{Th}1[{\mathrm{T}}_1^{\text{LN}}]$). Panel B: number of CD69+/CD4+ T cells in the LN ($(\text{Precursor}\text{Th}1[{\widehat{\mathrm{T}}}_1^{\text{LN}}]+\text{Th}1[{\mathrm{T}}_1^{\text{LN}}])$. Panel C: number of CD69+/CD4+T cells in the Lung (Precursor Th1 [T̂₁] +Th1 [ T₁ ]). Panel D: total number of CD8+T cells in the LN (Naïve CD8 [N₈]+Precursor effector CD8 $[{\mathrm{T}}_{80}^{\text{LN}}]+\text{IFN}-\mathrm{\gamma }$ producing CD8 $[{\mathrm{T}}_8^{\text{LN}}]+\text{CTL}[{\mathrm{T}}_{\mathrm{C}}^{\text{LN}}]$). Panel E: number of CD69+/CD8+ T cells in the LN (Precursor effector CD8 $[{\mathrm{T}}_{80}^{\text{LN}}]+\text{IFN}-\mathrm{\gamma }$ producing CD8 $[{\mathrm{T}}_8^{\text{LN}}]+\text{CTL}[{\mathrm{T}}_{\mathrm{C}}^{\text{LN}}]$. Panel F: number of CD69+/CD8+ T cells in the Lung (Precursor effector CD8 [ T₈₀ ]+IFN-γ producing CD8 [ T₈ ]+CTL [ T_C ]).