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. Author manuscript; available in PMC: 2011 Dec 23.
Published in final edited form as: Nature. 2011 May 25;474(7352):506–510. doi: 10.1038/nature10111

Figure 2. DLPC and DUPC modulate expression of LRH-1 target genes in liver.

Figure 2

a, , 8-week-old male C57BL/6 mice were challenged orally with vehicle, CA, DPPC, DUPC, and DLPC for 3 days. Total liver RNA was isolated and prepared for the cDNA. Hepatic gene expression was determined using qPCR. mRNA levels are relative to 36B4. b, Total BA pool and serum BAs, glucose, TG, NEFA, and cholesterol were measured in the same animals. c, Hepatic TG, NEFA, and cholesterol were measured in the same animals. Error bars represent mean ± s.e.m. (*P<0.05, **P<0.01 vs veh; n=5 animals/group).