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. Author manuscript; available in PMC: 2011 Aug 5.
Published in final edited form as: Nature. 2010 Sep 16;467(7313):285–290. doi: 10.1038/nature09342

Figure 3. Analysis of methylation in stem cell lines.

Figure 3

a, Cluster dendrogram using probes from DMRs that distinguish B-iPSC and F-iPSC. Cell clones are described in Supplemental Table 5. b, Enrichment of DMRs for hematopoiesis and fibroblast-related transcription factors in B-iPSC and F-iPSC, relative to chance (blue histogram; 100,000 random permutations). Left panel: 20 of 74 hematopoiesis-related transcription factors overlap DMRs hypermethylated in F-IPSC (p=0.0034); Right panel: 115 of 764 fibroblast-specific genes overlap DMRs hypermethylated in B-iPSC (p=10−5).