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. Author manuscript; available in PMC: 2012 Aug 15.
Published in final edited form as: J Immunol. 2011 Jul 18;187(4):1537–1541. doi: 10.4049/jimmunol.1100660

FIGURE 3.

FIGURE 3

Anti-PD-1H treatment robustly inhibits aGVHD. a) Lethally irradiated BDF1 mice received 5 × 106 TCD-BM + 3 × 106 pan T cells and 200 ug of hamIg (open triangles) or MH5A (closed squares) on day 0. inset) Analysis of chimerism at 30day by FACS analysis of circulating donor (H-2d negative) neutrophils (light gray), CD4+ T cells (dark gray) and CD8+ T cells (black bar). b) Lethally irradiated B6 mice received 5 × 106 BM + 1 × 107 total LN cells and 200μg hamIg (open triangles) or MH5A (closed squares) on day 0. inset) Analysis of chimerism at 30day for circulating donor (H-2d positive) neutrophils (light gray), CD4+ T cells (dark gray), and CD8+ T cells (black bar).