Fig. 1.

Crystal structure of astrovirus P2^415–646. (A) Side view of the P2^415–646 dimer. The two subunits are colored in red and blue, respectively. The N and C termini of the red subunit are highlighted by dotted lines. The viral capsid lies at the bottom the dimeric spike. (B) Top view of the P2^415–646 dimer. (C) Structure of one P2^415–646 molecule. The polypeptide is rainbow-colored with the N terminus in blue and the C terminus in red. (D and E) Surface representations of the P2^415–646 dimer for comparison with the cryo-EM reconstruction image. Molecules in D and E are viewed from the same orientation as in A and B, respectively. The figures were made with PyMOL (39).