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. 2011 Jul 18;108(31):12931–12936. doi: 10.1073/pnas.1104495108

Fig. 3.

Fig. 3.

D1/D5 and β-adrenergic receptors are required to trigger PRP synthesis, and NMDA-receptor activation is necessary for tagging in IA-LTM formation. All graphs show step-down latencies expressed as mean ± SEM. Training latency is representative for all groups. (A) OF exploration prevented the anterograde amnesia induced by the infusion of SCH into the CA1-dHP 10 min before sIA training. This preventive effect was impaired by Ani given immediately after OF exposure. ***P < 0.001 vs. training, SCH, and OF + Ani + SCH. (B) As in A but using Prop. (C) OF exploration did not prevent the anterograde amnesia induced by the infusion of AP5 in the CA1-dHP 10 min before sIA training. ***P < 0.001 vs. all groups. (D) OF exploration prevented the anterograde amnesia induced by the infusion of Ani in the CA1-dHP 10 min before sIA training. ***P < 0.001 vs. training and Ani.