Fig. 5.

Different views of the nascent-chain conduit in Pyrococcus furiosus SecYEβ (5) whose structure reveals a partially open (“primed”) translocon. (A) View along the membrane plane, showing the partially open lateral gate (yellow oval). (B) Same view as in A but with the front of the molecule removed to show the rear wall of the channel. (C) View of the upper parts of the channel (yellow oval) seen from the cytoplasmic end. The lateral gate is indicated by the arrow. Carbon atoms are displayed in white, oxygen atoms in red, nitrogen atoms in blue, and sulfur atoms in yellow.