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. 2011 Apr 9;2(2):53–63. doi: 10.4021/wjon301w

Figure 2.

Figure 2

Time-dependent reduction in animal body weight, tumor volume, and tumor weight in RD-ES xenografts following treatments. Treatments for 15 days: control (CTL), 4-HPR (20 µg/kg/day), GST (2 mg/kg/day), and 4-HPR (20 µg/kg/day) plus 4-h later GST (2 mg/kg/day). (A) Body weight changes; (B) tumor volume changes; and (C) tumor weight changes after therapies. Combination therapy showed best efficacy in reducing animal body weight and tumor volume. We used 6 animals per group (*P < 0.05 or **P < 0.001).