Table 1.
The time-dependent functions and growth, treatment parameters for the model.
| Functions within the model (time dependent) | |
| Rt | Average overall tumor radius (see Appendix) |
| δp | Proliferative rim thickness (determines growth fraction) |
| δn | Non-proliferative thickness (determines necrotic fraction) |
| pd | Probability of division (varies with time and position) |
| Growth parameters | |
| p0 | Base probability of division, linked to cell-doubling time (0.192) |
| a | Base necrotic thickness, controlled by nutritional needs (0.42 mm1/3) |
| b | Base proliferative thickness, controlled by nutritional needs (0.11 mm1/3) |
| Rmax | Maximum tumor extent, controlled by pressure response (38 mm) |