Table 2.
Treatment parameters and associated terms for the model.
| Treatment parameters | |
| γ | Governs the proliferative cells’ response at each instance of treatment (0.55 – 0.95) |
| ∊ | Allows for different treatment responses between proliferative and non-proliferative cells (0 – 0.4) |
| ϕ | Fraction of surviving proliferative cells that mutate in response to treatment (10−5 – 10−2) |
| Other Terms | |
| Dpro | Fraction of proliferative cells that die upon treatment; equivalent to γ |
| Dnon | Fraction of non-proliferative cells that die upon treatment; equivalent to γ∊ |
| β | Volumetric fraction of living cells (proliferative and non-proliferative) belonging to the secondary strain |