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. Author manuscript; available in PMC: 2012 Aug 1.
Published in final edited form as: Pflugers Arch. 2011 May 10;462(2):315–330. doi: 10.1007/s00424-011-0959-9

Table 1. Comparative ionic permeabilities via chord conductances at −180 mV.

Test Ion Conc. (mM) Figure no. pHo Size (ϕ) Im pA Gm pS aP/107 cm s−1
Cl 183 4 7.5 1.0 26.7 148 1.13
Br 175b 4 7.5 0.77 41.6 231 2.29
I 175 4 7.5 0.81 44.1 245 2.30
SCN 175c 7 7.5 1.0 35.2 196 1.49
NO3 175 7.5 1.0 45.8 254 1.94
SCN 30b 7 7.5 1.0 55.6 309 13.6
NO3 30 7.5 1.0 39.7 220 9.72
NO2 30d 5 7.5 1.0 52.6 416 12.9
Cl 183 4 5.5 1.0 105.0 583 4.45
Br 175b 4 5.5 0.77 85.6 476 4.70
I 175 4 5.5 0.81 90.7 504 4.74
SCN 175c 7 5.5 1.0 49.9 277 2.11
NO3 175 5.5 1.0 45.8 254 1.94
Formate 175 5.5 1.0 15.9 88.4 0.671
Gluconate 175 5.5 1.0 8.3 46.2 0.351
Acetate 175 5.5 1.0 4.6 25.5 0.194
H2PO4 170e 5.5 1.0 1.2 6.9 0.054
Cl 30b 2 5.5 1.27 30.3 168 5.83
SCN 30 7 5.5 1.0 42.7 237 10.5
NO3 30 5.5 1.0 39.7 220 9.72
NO2 30d 5 5.5 1.0 60.2 730 14.7
a

Formally, Gm] −180=−Im]−180/0.18, and the relevant permeability (e.g., for Cl) is PCl=(RT/2F2)×(Gm]−180)/[Cl]i, where the factor 2 represents the standard surface area, 2×10−6 cm2. PCl is normalized (÷ ϕ) for cell surface areas (see values in figure legends)

b

All buffer solutions contained 8.3 mM residual Cl, which was included in the total concentration used to calculate permeabilities, except for SCN and NO3. See legend to Fig. 4

c

For thiocyanate and nitrate, only their actual concentrations (175 and 30 mM) were used, assuming simultaneous blockade of chloride. See esp. legend to Fig. 7

d

Calculations done as if NO2 currents added to Cl currents appropriate for 153 mM. This would be the superchloride behavior suggested in the text description of Fig. 5

e

Corrected from 175 mM, due to second dissociation at pKa=7.2