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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Curr Comput Aided Drug Des. 2011 Jun 1;7(2):146–157. doi: 10.2174/157340911795677602

Figure 1.

Figure 1

Superimposed apo- (in yellow) and holo- (in blue) crystal structures of triosephosphate isomerase. PDB code 1YPI and 2YPI, respectively [116]. The 11 residue-loop composed of binding site is the only region that has large motion upon ligand binding (in circle).