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. 2011 Aug 5;6(8):e22405. doi: 10.1371/journal.pone.0022405

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Hayes et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The contour maps show collagen interfibrillar spacing (IFS) in an unswollen normal cornea (N3) and a slightly swollen keratoconus cornea (K2) before and after hypo-osmolar riboflavin/UVA cross-linking (Hypo-R CXL) and a normal unswollen cornea (N8) before and after iso-osmolar riboflavin/UVA cross-linking (Iso-R CXL). The centre of each corneal button corresponds approximately with the centre of each map.