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. 2011 Aug 5;6(8):e22405. doi: 10.1371/journal.pone.0022405

Table 1. Sample details and treatments.

Sample Hydration Classification Riboflavin/UVA treatment
Hypo-osmolar riboflavin/UVA cross-linking: Keratoconus
K1 2.2 Keratoconus; unswollen Hypo-osmolar
K2 3.8 Keratoconus; swollen Hypo-osmolar
Hypo-osmolar riboflavin/UVA cross-linking: Normal
N1 2.3 Normal; unswollen Hypo-osmolar
N2 2.4 Normal; unswollen Hypo-osmolar
N3 2.1 Normal; unswollen Hypo-osmolar
N4 2.5 Normal; unswollen Hypo-osmolar
N5 6.6 Normal; swollen Hypo-osmolar
N6 6.6 Normal; swollen Hypo-osmolar
Iso-osmolar riboflavin/UVA cross-linking: Normal
N7 2.0 Normal; unswollen Iso-osmolar
N8 1.9 Normal; unswollen Iso-osmolar
N9 2.5 Normal; unswollen Iso-osmolar
N10 5.7* Normal left; swollen Iso-osmolar
N11 5.7 Normal right; swollen None (control for N10)
N12 5.3* Normal left; swollen Iso-osmolar
N13 5.3 Normal right; swollen None (control for N12)
N14 5.2* Normal left; swollen Iso-osmolar
N15 5.2 Normal right; swollen None (control for N14)

Details of pre-treatment tissue hydration (recorded at the time of data collection), classification and UVA cross-linking treatment (hypo-osmolar/iso-osmolar riboflavin solution) are shown for each sample. Each cornea has been classified as being either ‘unswollen’ (at or below a physiological hydration of H = 3.2) or ‘swollen’ (above physiological hydration).

*The pre-treatment hydration of samples N10, N12 and N14 was assumed to be the same as that of their untreated pair (N11, N13 and N15 respectively).