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. 2011 Aug 5;6(8):e22490. doi: 10.1371/journal.pone.0022490

Table 5. Optimization results for the four test systems.

Proteins Functional Promoters Delay
Units (Repressed/Activated/Constitutive) Stages
Single-Not Unoptimized 4 4 4 (2/1/1) 3
Optimized 3 3 3 (2/0/1) 2
% Improvement 25% 25% 33% 33%
Three-Gate Unoptimized 10 10 9 (7/1/1) 5
Optimized 4 5 4 (3/0/1) 2
% Improvement 60% 50% 55% 60%
Quad-Not Unoptimized 7 7 7 (5/1/1) 6
Optimized 2 2 2 (1/0/1) 1
% Improvement 71% 71% 71% 83%
2-bit adder Unoptimized 55 56 53 (37/15/1) 12
Optimized 26 23 24 (19/4/1) 7
% Improvement 52% 59% 55% 42%