Table 1.
Baseline characteristics by presence or absence of CHD and depressive symptoms at phase 7
| Variables | N total | No CHD, not depressed | No CHD, Depressed | CHD, not depressed | CHD, depressed | P value/trend |
|---|---|---|---|---|---|---|
| Sex | 0.161 | |||||
| Male | 4268 | 3359 (72.9) | 491 (63.2) | 350 (79.0) | 68 (63.0) | |
| Female | 1668 | 1259 (27.1) | 286 (36.8) | 93 (21.0) | 40 (37.0) | |
| Age in years | < 0.001 | |||||
| < 54 | 1110 | 873 (18.9) | 203 (26.1) | 25 (5.6) | 9 (8.3) | |
| 54–59 | 1822 | 1453 (31.5) | 251 (32.3) | 97 (21.9) | 21 (19.4) | |
| 60–64 | 1259 | 998 (21.7) | 140 (18.0) | 98 (22.1) | 23 (21.3) | |
| 64–69 | 1196 | 896 (19.4) | 129 (16.6) | 137 (30.9) | 34 (31.5) | |
| 70–74 | 549 | 388 (8.4) | 54 (6.9) | 86 (19.4) | 21 (19.4) | |
| SEP | < 0.001 | |||||
| High | 2040 | 1661 (36.0) | 181 (23.3) | 178 (40.2) | 20 (18.5) | |
| Middle | 3032 | 2361 (51.2) | 415 (53.4) | 202 (45.6) | 54 (50.0) | |
| Low | 864 | 586 (12.7) | 181 (23.3) | 63 (14.2) | 34 (31.5) | |
| Ethnicity | < 0.001 | |||||
| White | 5485 | 4355 (94.3) | 669 (86.1) | 397 (89.6) | 74 (68.5) | |
| Other | 451 | 263 (5.7) | 108 (13.9) | 46 (10.4) | 34 (31.5) | |
| Antidepressant drugs | < 0.001 | |||||
| No | 5728 | 4505 (97.8) | 690 (88.8) | 437 (98.6) | 96 (88.9) | |
| Yes | 208 | 103 (2.2) | 87 (11.2) | 6 (1.4) | 12 (11.1) | |
| Smoking status | 0.001 | |||||
| Never smoker | 2678 | 2129 (46.2) | 334 (43.0) | 172 (38.8) | 43 (39.8) | |
| Ex smoker | 2282 | 1780 (38.6) | 255 (32.8) | 205 (46.3) | 42 (38.9) | |
| Current smoker | 680 | 490 (10.6) | 132 (17.0) | 45 (10.2) | 13 (12.0) | |
| Missing | 296 | 209 (4.5) | 56 (7.2) | 21 (4.7) | 10 (9.3) | |
| Alcohol consumption | 0.994 | |||||
| Abstainers | 973 | 662 (14.4) | 179 (23.0) | 91 (20.5) | 41 (38.0) | |
| Moderate | 3725 | 2983 (64.7) | 437 (56.2) | 258 (58.2) | 47 (43.5) | |
| High | 1158 | 920 (20.0) | 137 (17.6) | 85 (19.2) | 16 (14.8) | |
| Missing | 80 | 43 (0.9) | 24 (3.1) | 9 (2.0) | 4 (3.7) | |
| Exercise | < 0.001 | |||||
| ≥ 1.5 h/week | 5152 | 4074 (88.4) | 625 (80.4) | 379 (85.6) | 74 (68.5) | |
| < 1.5 h/week | 784 | 534 (11.6) | 152 (19.6) | 64 (14.4) | 34 (31.5) | |
| Hypertension | < 0.106 | |||||
| No | 4521 | 3590 (76.4) | 603 (77.6) | 324 (73.2) | 74 (68.5) | |
| Yes | 1410 | 1084 (23.5) | 174 (22.4) | 118 (26.6) | 34 (31.5) | |
| Missing | 5 | 4 (0.1) | 0 (0.0) | 1 (0.2) | 0 (0.0) | |
| BMI (kg/m2) | < 0.001 | |||||
| < 20 | 179 | 133 (2.9) | 37 (4.8) | 8 (1.8) | 1 (0.9) | |
| 20–24.9 | 2028 | 1638 (35.5) | 241 (31.0) | 127 (28.7) | 22 (20.4) | |
| 25–29.9 | 2606 | 2047 (44.4) | 320 (41.2) | 194 (43.8) | 45 (41.7) | |
| ≥ 30 | 1099 | 773 (16.8) | 176 (22.7) | 112 (25.3) | 38 (35.2) | |
| Missing | 24 | 17 (0.4) | 3 (0.4) | 2 (0.5) | 2 (1.9) | |
| Diabetes | < 0.001 | |||||
| No | 5656 | 4442 (96.4) | 727 (93.6) | 397 (89.6) | 89 (82.4) | |
| Yes | 281 | 166 (3.6) | 50 (6.4) | 46 (10.4) | 19 (17.6) | |
| High total cholesterol | < 0.001 | |||||
| No | 1335 | 912 (19.8) | 178 (22.9) | 197 (44.5) | 48 (44.4) | |
| Yes | 4491 | 3639 (79.0) | 583 (75.0) | 216 (48.7) | 53 (49.1) | |
| Missing | 110 | 57 (1.2) | 16 (2.1) | 30 (6.8) | 7 (6.5) | |
| Resting Heart Rate > 80 bpm | 0.803 | |||||
| No | 5051 | 3929 (85.3) | 648 (83.4) | 384 (86.7) | 90 (83.3) | |
| Yes | 885 | 679 (14.7) | 129 (16.6) | 59 (13.3) | 18 (16.7) | |
| CVD medications (Yes) | ||||||
| Diuretics | 494 | 348 (7.6) | 54 (6.9) | 70 (15.8) | 22 (20.4) | < 0.001 |
| Beta Blockers | 584 | 346 (7.5) | 60 (7.7) | 147 (33.2) | 31 (28.7) | < 0.001 |
| ACE Inhibitors | 649 | 392 (8.5) | 76 (9.8) | 144 (33.2) | 34 (31.5) | < 0.001 |
| Calcium Channel Blockers | 420 | 259 (5.6) | 43 (5.5) | 94 (21.2) | 24 (22.2) | < 0.001 |
| Other anti-hypertensive | 99 | 72 (1.6) | 8 (1.0) | 14 (3.2) | 5 (4.6) | 0.009 |