Table 4.
Results from multiple logistic regression for maternal MAOA of male children.
AU | AU+ASD | |||||
---|---|---|---|---|---|---|
MAOA | OR | 95% CI | P | OR | 95% CI | P |
Additive | 1.76 | 1.13,2.74 | 0.01 | 1.72 | 1.14,2.60 | 0.009 |
Dominant | 2.24 | 0.93,5.39 | 0.07 | 2.59 | 1.15,5.83 | 0.02 |
Recessive | 2.03 | 1.10,3.72 | 0.02 | 1.78 | 1.01,3.12 | 0.04 |
General | 0.04 | 0.03 | ||||
Het | 1.71 | 0.68,4.32 | 0.26 | 2.15 | 0.92,5.04 | 0.08 |
Hom | 3.07 | 1.19,7.91 | 0.02 | 3.26 | 1.35,7.89 | 0.009 |
Multiple logistic regression of disease and marker adjusted for ethnicity and maternal age, using White and Hispanic index children only.
Additive refers to additive genetic model for which the OR shows the effects of heterozygous genotype (eg. 34 or 43) on autism risk as compared to those of homozygous genotype for the major allele (eg. 33); the effects of homozygous genotype (eg. 44) will be 2*OR.
Dominant refers to dominant genetic model where subjects with heterozygous or homozygous genotype for allele 4 were compared with those with homozygous genotype for allele 3.
Recessive refers to recessive genetic model where subjects with homozygous genotype for allele 4 were compared to those with either hyterozygous or homozygous genotype for allele 3.
General refers to the general genetic model where subjects with heterozygous and homozygous genotypes for allele 4 were compared with those with homozygous genotype for allele 3 respectively.