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. 2011 Sep 15;15(6):1567–1582. doi: 10.1089/ars.2010.3740

FIG. 5.

FIG. 5.

Biochemical pathways and inter-relationships between different oxidative species. Superoxide (Inline graphic), GSH, GSSG, glutathione peroxidase (GSH-Px), glutathione reductase (GSH-Red.), total nitric oxide synthase (tNOS), nitric oxide (NO), peroxynitrite (ONOO), hydrogen peroxide (H2O2), hydroxide anion (OH), hydroxyl radical (OH), polyunsaturated fatty acid (PUFA), oxidized nicotinamide adenine dinucleotide phosphate (NADP+), adenosine monophosphate (AMP), and adenosine 5′-diphosphoribose (ADPR). Modified from Naziroğlu (80). (To see this illustration in color the reader is referred to the web version of this article at www.liebertonline.com/ars).