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. 2011 Sep 15;15(6):1739–1748. doi: 10.1089/ars.2010.3650

FIG. 2.

FIG. 2.

Some of the proposed pathways by which exercise inhibits cancer are summarized using the multistep model of carcinogenesis (86). Such a model provides a useful framework for outlining the complex network of cellular processes affecting initiation and promotion/progression of cancer formation. The strength of evidence supporting the specific mechanisms is variable.