Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The suppression of anaerobic metabolism by p53 is mediated through multiple pathways. Glycolysis is inhibited by decreasing metabolic substrate availability through downregulation of glucose transporters and by modulating key enzymes in the glycolytic pathway hexokinase 2 (HK2), 6-phosphofructo-1-kinase (PFK-1), and phosphoglycerate mutase (PGM).
