TABLE 6.

Serum concentrations of glucose, lipids, insulin, and leptin in 31-wk-old rats at the end of a 12-wk period of receiving a LF or HF diet and water containing either 1.51% l-arginine·HCl or 2.55% l-alanine ¹

	Groups				P-value
Variables	LF-Ala	LF-Arg	HF-Ala	HF-Arg	Diet	AA	Diet × AA
Glucose, mmol/L	5.99 ± 0.09a	5.76 ± 0.15b	6.08 ± 0.15a	5.74 ± 0.13b	0.81	0.04	0.69
Triglycerides, mmol/L	0.93 ± 0.11a	0.68 ± 0.07b	1.05 ± 0.08a	0.66 ± 0.07b	0.57	<0.01	0.45
Cholesterol, mmol/L	4.80 ± 0.27b	4.45 ± 0.19b	6.27 ± 0.54a	7.11 ± 0.41a	<0.01	0.54	0.10
FFA, mmol/L	0.81 ± 0.12	0.62 ± 0.07	0.80 ± 0.13	0.72 ± 0.09	0.68	0.23	0.61
Insulin, pmol/L	95.9 ± 7.1	116 ± 9.6	113 ± 9.0	105 ± 13	0.62	0.56	0.20
Leptin, μg/L	7.73 ± 1.22b	3.35 ± 0.36c	9.22 ± 1.41a	7.28 ± 0.94b	0.02	<0.01	0.27
Urea, mmol/L	2.64 ± 0.11a	2.05 ± 0.25b	2.35 ± 0.14a	1.94 ± 0.10b	0.23	<0.01	0.69
NOx,2μmol/L	20.7 ± 0.81b	29.2 ± 1.1a	17.1 ± 0.90c	27.6 ± 1.2a	0.01	<0.01	0.41

¹Values are means ± SEM, n = 8. Means in a row with superscripts without a common letter differ, P < 0.05.

²NO metabolites (nitrite plus nitrate).