Table 2.
Age adjusted odds ratios for sample characteristics and moderate or severe self-reported sleep difficulty, age 48 – 541
| Moderate versus None (95% CI)2 |
P value4 | Severe versus None (95% CI)3 |
P value4 | |
|---|---|---|---|---|
| Age (per year increase) | 1.07 (1.04, 1.10) | < 0.01 | 1.08 (1.04, 1.12) | < 0.01 |
| Symptoms | ||||
| vasomotor symptoms | ||||
| No | 1.00 | < 0.01 | 1.00 | < 0.01 |
| Yes | 1.64 (1.44, 1.88) | 2.12 (1.76, 2.55) | ||
| somatic symptoms (0 - 21) | ||||
| 0 - 2 | 1.00 | < 0.01 | 1.00 | < 0.01 |
| 3 - 4 | 1.52 (1.25, 1.84) | 2.08 (1.43, 3.01) | ||
| 5 - 7 | 2.51 (2.06, 3.06) | 4.91 (3.39, 7.12) | ||
| ≥ 8 | 3.98 (3.21, 4.94) | 11.03 (7.50, 16.21) | ||
| waking to use the toilet at night | ||||
| No | 1.00 | < 0.01 | 1.00 | < 0.01 |
| Yes | 1.55 (1.29, 1.85) | 2.07 (1.66, 2.57) | ||
| psychological symptoms (0 - 15) | ||||
| 0-1 | 1.00 | < 0.01 | 1.00 | < 0.01 |
| 2-3 | 2.05 (1.52, 2.77) | 2.43 (1.44, 4.11) | ||
| 4-5 | 2.69 (1.99, 3.54) | 3.78 (2.27, 6.32) | ||
| ≥ 6 | 2.99 (2.22, 4.04) | 6.48 (3.96, 10.60) | ||
| Life events | ||||
| Work-related (number) | ||||
| 0 | 1.00 | < 0.01 | 1.00 | < 0.01 |
| 1 | 1.27 (1.11, 1.47) | 1.61 (1.33, 1.95) | ||
| 2 | 1.62 (1.32, 1.99) | 2.09 (1.61, 2.70) | ||
| 3 | 2.16 (1.68, 2.76) | 3.93 (2.97, 5.20) | ||
| Family-related (number) | ||||
| 0 | 1.00 | < 0.01 | 1.00 | < 0.01 |
| 1 | 1.33 (1.15, 1.54) | 1.45 (1.19, 1.77) | ||
| 2 | 1.68 (1.38, 2.03) | 2.21 (1.72, 2.83) | ||
| 3 | 1.87 (1.45, 2.40) | 2.41 (1.77, 3.27) | ||
| 4 | 2.94 (2.20, 3.93) | 3.65 (2.63, 5.06) | ||
| Education at Age 26 Years | ||||
| None | 1.00 | 0.07 | 1.00 | 0.83 |
| Lower secondary level qualifications |
0.98 (0.77, 1.25) | 0.79 (0.56, 1.11) | ||
| Advanced secondary | 1.30 (1.00, 1.69) | 1.04 (0.72, 1.51) | ||
| Degree level or equivalent | 1.20 (0.79, 1.81) | 0.80 (0.43, 1.50) | ||
| Marital Status at Age 43 Years | ||||
| Not married | 1.00 | 0.21 | 1.00 | 0.76 |
| Married | 1.18 (0.91, 1.54) | 0.94 (0.66, 1.35) | ||
| Number of Children at Age 53 Years |
||||
| 0 | 0.62 (0.45, 0.86) | 0.06 | 0.68 (0.43, 1.10) | 0.26 |
| 1 | 0.93 (0.68, 1.28) | 1.09 (0.70, 1.70) | ||
| 2 | 1.00 | 1.00 | ||
| 3 | 0.87 (0.67, 1.12) | 1.01 (0.70, 1.45) | ||
| ≥ 4 | 1.05 (0.72, 1.55) | 1.04 (0.60. 1.80) | ||
| Psychiatric Symptom Frequency Score at Age 43 Years (0 - 90) |
||||
| 0 - 4 | 1.00 | < 0.01 | 1.00 | < 0.01 |
| 5 - 9 | 2.05 (1.52, 2.77) | 2.43 (1.44, 4.11) | ||
| 10 - 16 | 2.69 (1.99, 3.64) | 3.78 (2.27, 6.32) | ||
| ≥ 17 | 2.99 (2.22, 4.04) | 6.48 (3.96, 10.60) | ||
| Number of Physical Conditions at Age 43 Years (0 - 9) |
||||
| 0 | 1.00 | < 0.01 | 1.00 | < 0.01 |
| 1 | 1.37 (1.09, 1.72) | 1.62 (1.15, 2.27) | ||
| ≥ 2 | 1.63 (1.27, 2.10) | 2.43 (1.70, 3.46) | ||
| History of Trouble Sleeping at Age 43 Years |
||||
| No | 1.00 | < 0.01 | 1.00 | < 0.01 |
| Yes | 2.31 (1.79, 3.00) | 4.06 (2.96, 5.57) | ||
| Use of Prescription Medication at Age 43 Years (0 - 7) |
||||
| 0 | 1.00 | < 0.01 | 1.00 | < 0.01 |
| 1 | 1.50 (1.20, 1.88) | 1.90 (1.38, 2.62) | ||
| ≥ 2 | 1.31 (0.98, 1.75) | 2.23 (1.51, 3.28) | ||
| Exercise at Age 43 Years | ||||
| Inactive | 1.00 | 0.37 | 1.00 | 0.12 |
| Vigorous < 1x/week | 1.11 (0.87, 1.42) | 0.91 (0.64, 1.30) | ||
| Vigorous > 1x/week | 1.10 (0.86, 1.41) | 0.74 (0.51, 1.08) | ||
| Ever Smoked at Age 43 Years | ||||
| No | 1.00 | 0.20 | 1.00 | 0.04 |
| Yes | 1.14 (0.93, 1.39) | 1.35 (1.02, 1.80) | ||
| Alcohol Consumption in Drinks/day at Age 43 Years |
||||
| 0 | 1.00 | 0.77 | 1.00 | 0.6 |
| 0.1 - 1.0 | 1.07 (0.85, 1.34) | 0.87 (0.62, 1.2) | ||
| 1.1 - 2.0 | 0.83 (0.61, 1.13) | 0.84 (0.54, 1.30) | ||
| ≥ 2.1 | 1.09 (0.75, 1.57) | 0.96 (0.57, 1.62) | ||
| Body Mass Index at Age 43 Years | ||||
| <18.5 | 1.00 | 0.97 | 1.00 | 0.04 |
| 18.5-24.9 | 1.35 (0.89, 2.03) | 1.27 (0.69, 2.34) | ||
| 25-29.9 | 1.35 (0.87, 2.08) | 1.52 (0.80, 2.89) | ||
| ≥ 30 | 1.13 (0.69, 1.85) | 1.82 (0.91, 2.66) |
1
Unless otherwise indicated, the variable was measured annually between ages 48 – 54 years
2
N = 938, observations = 4072
3
N = 888, observations = 3125
4
p value for test of heterogeneity for menopausal transition status, test of linear trend for all other categorical variables, and Wald test for binary variables.