Table 2.
Alcohol use, problems, and depressive symptoms by 5-HTTLPR genotype1 [M ± (SD)].
| SS/SL (n = 44) | LL (n = 28) | SS/LL vs. LL | |
|---|---|---|---|
| RAPI total score (possible range: 0–69) |
17.2 (12.96) | 28.22 (17.73) |
t(70) = −3.04; p = 0.010* |
| BDI-II total score (possible range: 0–63) |
7.25 (7.03) | 8.82 (7.69) |
t(70) = −0.892; p = 0.376 |
| Drinks per drinking day in the past 30 days | 5.75 (2.57) | 7.12 (3.64) |
t(70) = 1.386; p = 0.173 |
| Drinking days in the past 30 days | 9.20 (5.55) | 11.67 (5.64) |
t(70) = 1.90; p = 0.062a |
| Binge-drinking days in the past 30 days | 5.76 (4.54) | 8.26 (5.70) |
t(70) = 1.954; p = 0.055a |
| Total drinks in the past 30 days | 55.86 (43.88) | 90.78 (72.05) |
t(70) = 2.23; p = 0.031* |
1Genotype was coded as: SS/SL = 1, LL = 0.
*Significant results are starred.
aTrend-level finding.
Analyses were repeated with ethnicity as a covariate. Genotype remained a significant predictor of RAPI score (p = 0.017). The addition of ethnicity to the model reduced the significance of genotype as a predictor of total drinks to p = 0.074.