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Chronic progressive course of clinical EAE. C57/BL6 mice were immunized with MOG on day 0 and injected with pertussis toxin on day 0 and 2. Mice were observed daily for clinical signs of EAE. Clinical EAE was first detected at day 8 after immunization, and increased through day 17 before reaching a chronic level. One of four experiments is shown. Data represent average (mean ± SEM) EAE score of n = 6 mice.
