Fig. 5.

TG turnover in apoE isoform knock-in adipocytes. A: TG synthesis was measured in apoE2, -E3, and -E4 freshly isolated mature adipocytes in the absence or presence of 100 μg/ml human VLDL isolated from an apoE3/E3 donor, as described in Materials and Methods. B: TG hydrolysis was measured in freshly isolated mature adipocytes isolated from apoE isoform mice as described in Materials and Methods. *P < 0.05, **P < 0.01 for comparison to E3 under the same incubation conditions.