TABLE 2.

Treatment effects of simvastatin 80 mg in FH patients

	Baseline n = 514	After Two Years n = 436	% Change	Pa
TC (mmol/L)	10.52 ± 2.17	6.30 ± 1.41	−39.2 ± 11.8	<0.0001
LDL cholesterol (mmol/L)	8.38 ± 2.14	4.29 ± 1.31	−48.0 ± 13.5	<0.0001
HDL cholesterol (mmol/L)	1.23 ± 0.35	1.36 ± 0.36	12.7 ± 21.8	<0.0001
Triglycerides (mmol/L)	1.80 (1.20 to 2.40)	1.20 (0.90 to 1.70)	−26.3 (−46.2 to −5.6)	<0.0001
Total bilirubin (μmol/L)	10.0 (7.8 to 12.8)	10.8 (7.8 to 13.7)	7.0 (−14.1 to 31.1)	<0.0001
ASAT (U/l)	20 (17 to 24)	23 (19 to 27)	14 (0 to 32)	<0.0001

All values are given as median with IQR between brackets; only TC, LDL-C, and HDL-C levels are given as mean levels ± SD.

^aBaseline versus after two years.