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. Author manuscript; available in PMC: 2012 Aug 1.
Published in final edited form as: Cancer Prev Res (Phila). 2011 May 16;4(8):1325–1332. doi: 10.1158/1940-6207.CAPR-11-0017

FIGURE 6.

FIGURE 6

S1P2 antagonist JTE-013 inhibited growth of NB xenografts. A, The tumor growth curves of control and JTE-013-treated mice (n=7). B, VEGF mRNA levels in control and JTE-013-treated tumors by quantitative real-time PCR. C, Vessel density in control and JTE-013-treated tumors by PECAM-1 staining. D, Apoptotic cells in control and JTE-013-treated tumors labeled by TUNEL method. *, P < 0.05, **, P < 0.01 versus the corresponding control.