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. 2011 Apr 7;39(14):6172–6185. doi: 10.1093/nar/gkr100

Figure 1.

Figure 1.

Structure of the FMR1 5′-UTR in human and mouse brain. (A) Nucleotide position of the tss in both human and mouse. The tss are numbered to the left with respect to the translation codon (+1 ATG, 13967 nt) on a sequence reference (for human access number: L29074: for mouse access number AY630338). (B) Scheme of the tss in human (I, II, III and IV) and mouse (I and II). The asterisk marks the new tss. (C) Sequence comparison between human and mouse 5′-UTRs. The four human (h site I, II, III and IV) and the two mouse (m sites I and II) tss are bolded, in black and grey, respectively. The newly identified human transcription start site IV is underlined. The box represents the previously described Internal Ribosome Entry Site (IRES) (61,62). The alignment was performed using the ClustalW software.