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The zim17Δ mutants are sensitive to HU-mediated replicative stress in the absence of Rad24, Ctf18 and Mus81. (A) Schematic representation of the replicon. Allelic mutants are indicated by circles. (B) Drop-test analysis of serial dilutions was performed in YEPD plates in the absence or presence of 100 or 150 mM HU (asterisks). (C) Recombination rates of zim17Δ and rad24Δ zim17Δ mutants determined by the leu2-k system. For details see Figure 1A.
