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Cell-cycle progression is affected in zim17Δ and rad24Δ zim17Δ mutants. FACS analysis of S and G2 phase progression for (A) cells synchronized in G1/S for 3.5 h in the presence of α-factor or (B) treated for 90 min with nocodazole prior to release into YEPD medium. The fractions of unreplicated (1 n) or replicated (2 n) cells are indicated below (1 n + 2 n = 100).
