Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Illustration of DDX6 and HIF-1α regulation by miR-130. HIF-1α mRNA is accompanied by DDX6 to P-bodies which restrict translation with other P-body components under normoxia. Under hypoxia, DDX6 protein levels are decreased by the miR-130 family, and then HIF-1α is released from the P-bodies and facilitates IRES-dependent translation.
