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Close-up views of Fpg active site region in both LRC and DPC complex (a) Hyd lesion atom nomenclature. (b and c) View showing σA-weighted 2Fo − Fc simulated annealing omit maps contoured at 1.3 SD for LRC and DPC complexes, respectively. Elements of protein (gray) and DNA (blue or pink) are represented in stick models with oxygen, nitrogen and phosphate atoms colored in red, dark blue and orange, respectively. (d) Superimposition of both LRC and DPC crystal structures.
